Guidelines for sedation and anesthesia in GI endoscopy
Jan 30, 2018, 15:03 PM
This document is an update of guidelines for sedation and anesthesia in endoscopy prepared by the Standards of Practice Committee of the American Society for Gastrointestinal Endoscopy (順秞湮圖). In preparing this guideline, a search of the medical literature was performed by using PubMed from January 1980 through August 2017 that related to the topic of sedation and anesthesia for gastrointestinal endoscopy by using the keyword(s) sedation, anesthesia, gastrointestinal endoscopy, endoscopy, endoscopic procedures, and procedures. The search was supplemented by accessing the related articles feature of PubMed, with articles identified on PubMed as the references. Pertinent studies published in English were reviewed. Additional references were obtained from the bibliographies of the identified articles and from recommendations of expert consultants. When little or no data existed from well-designed prospective trials, emphasis was given to results from large series and reports from recognized experts. Guidelines for appropriate use of endoscopy are based on a critical review of the available data and expert consensus at the time the guidelines were drafted. Further controlled clinical studies may be needed to clarify aspects of this guideline. This guideline may be revised as necessary to account for changes in technology, new data, or other aspects of clinical practice. The recommendations were based on reviewed studies and were graded on the strength of the supporting evidence by using the GRADE criteria (Table 1).1
順秞湮圖 Standards of Practice Committee, Dayna S. Early, MD, F順秞湮圖
, Jenifer R. Lightdale, MD, MPH, F順秞湮圖
, John J. Vargo II, MD, MPH, F順秞湮圖 (invited content expert, ad hoc member)
, Ruben D. Acosta, MD
, Vinay Chandrasekhara, MD
, Krishnavel V. Chathadi, MD
, John A. Evans, MD
, Deborah A. Fisher, MD, MHS, F順秞湮圖
, Lisa Fonkalsrud, BSN, RN, CGRN
, Joo Ha Hwang, MD, PhD, F順秞湮圖
, Mouen A. Khashab, MD
, V. Raman Muthusamy, MD, F順秞湮圖
, Shabana F. Pasha, MD, F順秞湮圖
, John R. Saltzman, MD, F順秞湮圖
, Amandeep K. Shergill, MD
, Brooks D. Cash, MD, F順秞湮圖 (Previous Committee Chair)
, John M. DeWitt, MD, F順秞湮圖 (Committee Chair)
Guyatt, G.H., Oxman, A.D., Vist, G.E. et al. GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ. 2008; 336: 924926
View in Article | Crossref | PubMed
Practice guidelines for sedation and analgesia by non-anesthesiologists. Anesthesiology. 2002; 96: 10041017
View in Article | Crossref | PubMed | Scopus (1241)
Faigel, D.O., Baron, T.H., Goldstein, J.L. et al. Guidelines for the use of deep sedation and anesthesia for GI endoscopy. Gastrointest Endosc. 2002; 56: 613617
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (164)
Vargo, J.J., Cohen, L.B., Rex, D.K. et al. Position statement: nonanesthesiologist administration of propofol for GI endoscopy. Gastrointest Endosc. 2009; 70: 10531059
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (71)
Vargo, J.J., DeLegge, M.H., Feld, A.D. et al. Multisociety sedation curriculum for gastrointestinal endoscopy. Gastrointest Endosc. 2012; 76: e1e25
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (52)
Waring, J.P., Baron, T.H., Hirota, W.K. et al. Guidelines for conscious sedation and monitoring during gastrointestinal endoscopy. Gastrointest Endosc. 2003; 58: 317322
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (236)
Chutkan, R., Cohen, J., Abedi, M. et al. Training guideline for use of propofol in gastrointestinal endoscopy. Gastrointest Endosc. 2004; 60: 167172
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (90)
Zuckerman, M.J., Shen, B., Harrison, M.E. 3rd et al. Informed consent for GI endoscopy. Gastrointest Endosc. 2007; 66: 213218
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (43)
Godwin, S.A., Burton, J.H., Gerardo, C.J. et al. Clinical policy: procedural sedation and analgesia in the emergency department. Ann Emerg Med. 2014; 63: 247258.e18
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (71)
Practice guidelines for preoperative fasting and the use of pharmacologic agents to reduce the risk of pulmonary aspiration: application to healthy patients undergoing elective procedures: an updated report by the American Society of Anesthesiologists Committee on Standards and Practice Parameters. Anesthesiology. 2011; 114: 495511
View in Article | Crossref | PubMed | Scopus (368)
Khiani, V.S., Soulos, P., Gancayco, J. et al. Anesthesiologist involvement in screening colonoscopy: temporal trends and cost implications in the Medicare population. Clin Gastroenterol Hepatol. 2012; 10: 5864.e1
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (34)
Cha, J.M., Jeun, J.W., Pack, K.M. et al. Risk of sedation for diagnostic esophagogastroduodenoscopy in obstructive sleep apnea patients. World J Gastroenterol. 2013; 19: 47454751
View in Article | Crossref | PubMed | Scopus (11)
順秞湮圖 Standards of Practice Committee, Pasha, S.F., Acosta, R., Chandrasekhara, V. et al. Routine laboratory testing before endoscopic procedures. Gastrointest Endosc. 2014; 80: 2833
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (9)
順秞湮圖 Standards of Practice Committee, Shergill, A.K., Ben-Menachem, T., Chandrasekhara, V. et al. Guidelines for endoscopy in pregnant and lactating women. Gastrointest Endosc. 2012; 76: 1824
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (42)
American Society of Anesthesiology Physical Status Classification System 2014. Available at: http://www.asahq.org/resources/clinical-information/asa-physical-status-classification-system. Accessed April 19, 2015.
Enestvedt, B.K., Eisen, G.M., Holub, J. et al. Is the American Society of Anesthesiologists classification useful in risk stratification for endoscopic procedures?. Gastrointest Endosc. 2013; 77: 464471
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (29)
Sharma, V.K., Nguyen, C.C., Crowell, M.D. et al. A national study of cardiopulmonary unplanned events after GI endoscopy. Gastrointest Endosc. 2007; 66: 2734
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (209)
Ragsdale, J.A. Validating patient safety in the endoscopy unit using the Joint Commission Standards. Gastroenterol Nurs. 2011; 34: 218223
View in Article | Crossref | PubMed | Scopus (1)
American College of Surgeons. Statement on ensuring correct patient, correct site, and correct procedure surgery 2002. Available at https://www.facs.org/about-acs/statements/41-correct-patient-procedure. Accessed June 14, 2015.
Calderwood, A.H., Chapman, F.J., Cohen, J. et al. Guidelines for safety in the gastrointestinal endoscopy unit. Gastrointest Endosc. 2014; 79: 363372
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (27)
Bell, G.D., Bown, S., Morden, A. et al. Prevention of hypoxaemia during upper-gastrointestinal endoscopy by means of oxygen via nasal cannulae. Lancet. 1987; 1: 10221024
View in Article | Abstract | PubMed | Scopus (99)
Gerstenberger, P.D. Capnography and patient safety for endoscopy. Clin Gastroenterol Hepatol. 2010; 8: 423425
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (10)
Lightdale, J.R., Goldmann, D.A., Feldman, H.A. et al. Microstream capnography improves patient monitoring during moderate sedation: a randomized, controlled trial. Pediatrics. 2006; 117: 11701178
View in Article | Crossref | PubMed | Scopus (163)
Qadeer, M.A., Vargo, J.J., Dumot, J.A. et al. Capnographic monitoring of respiratory activity improves safety of sedation for endoscopic cholangiopancreatography and ultrasonography. (quiz 819-20)Gastroenterology. 2009; 136: 15681576
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (129)
Vargo, J.J. 2nd. Sedation-related complications in gastrointestinal endoscopy. Gastrointest Endosc Clin N Am. 2015; 25: 147158
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (5)
Friedrich-Rust, M., Welte, M., Welte, C. et al. Capnographic monitoring of propofol-based sedation during colonoscopy. Endoscopy. 2014; 46: 236244
View in Article | Crossref | PubMed | Scopus (1)
Mehta PP, Kochhar G, Albeldawi M, et al. Capnographic monitoring in routine EGD and colonoscopy with moderate sedation: a prospective, randomized, controlled trial. Am J Gastroenterol. Epub 2016 Feb 23.
Cohen, L.B., Ladas, S.D., Vargo, J.J. et al. Sedation in digestive endoscopy: the Athens international position statements. Aliment Pharmacol Ther. 2010; 32: 425442
View in Article | Crossref | PubMed | Scopus (50)
Petrini, J.L., Egan, J.V., and Hahn, W.V. Unsedated colonoscopy: patient characteristics and satisfaction in a community-based endoscopy unit. Gastrointest Endosc. 2009; 69: 567572
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (38)
Leung, F.W. and Aljebreen, A. Health care providers' acceptance of unsedated colonoscopy before and after a state-of-the-art lecture on the feasibility of the option. Saudi J Gastroenterol. 2012; 18: 5054
View in Article | Crossref | PubMed | Scopus (0)
Ai, Z.L., Lan, C.H., Fan, L.L. et al. Unsedated transnasal upper gastrointestinal endoscopy has favorable diagnostic effectiveness, cardiopulmonary safety, and patient satisfaction compared with conventional or sedated endoscopy. Surg Endosc. 2012; 26: 35653572
View in Article | Crossref | PubMed | Scopus (7)
Rex, D.K., Imperiale, T.F., and Portish, V. Patients willing to try colonoscopy without sedation: associated clinical factors and results of a randomized controlled trial. Gastrointest Endosc. 1999; 49: 554559
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (145)
Paggi, S., Radaelli, F., Amato, A. et al. Unsedated colonoscopy: an option for some but not for all. Gastrointest Endosc. 2012; 75: 392398
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (12)
Hedenbro, J.L. and Lindblom, A. Patient attitudes to sedation for diagnostic upper endoscopy. Scand J Gastroenterol. 1991; 26: 11151120
View in Article | Crossref | PubMed | Scopus (29)
Ladas, S.D. Factors predicting the possibility of conducting colonoscopy without sedation. Endoscopy. 2000; 32: 688692
View in Article | Crossref | PubMed | Scopus (23)
Bell, G.D. Preparation, premedication, and surveillance. Endoscopy. 2004; 36: 2331
View in Article | Crossref | PubMed | Scopus (47)
Wu, J. and Hu, B. The role of carbon dioxide insufflation in colonoscopy: a systematic review and meta-analysis. Endoscopy. 2012; 44: 128136
View in Article | Crossref | PubMed | Scopus (65)
Cadoni, S., Falt, P., Gallittu, P. et al. Water exchange is the least painful insertion technique and increases completion of unsedated colonoscopy. Clin Gastroenterol Hepatol. 2015; 13: 19721980
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (20)
Evans, L.T., Saberi, S., Kim, H.M. et al. Pharyngeal anesthesia during sedated EGDs: Is the spray beneficial? A meta-analysis and systematic review. Gastrointest Endosc. 2006; 63: 761766
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (47)
de la Morena, F., Santander, C., Esteban, C. et al. Usefulness of applying lidocaine in esophagogastroduodenoscopy performed under sedation with propofol. World J Gastrointest Endosc. 2013; 16: 231239
View in Article | Crossref
Tsai, H., Tsai, Y.F., Liou, S.C. et al. The questionable efficacy of topical pharyngeal anesthesia in combination with propofol sedation in gastroscopy. Dig Dis Sci. 2012; 57: 25192526
View in Article | Crossref | PubMed | Scopus (3)
Zakko, S.F., Seifert, H.A., and Gross, J.B. A comparison of midazolam and diazepam for conscious sedation during colonoscopy in a prospective double-blind study. Gastrointest Endosc. 1999; 49: 684689
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (52)
Geller, E. From oral midazolam to propofol: a perspective. Gastrointest Endosc. 2005; 61: 201203
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (5)
Cohen, J., Haber, G.B., Dorais, J.A. et al. A randomized, double-blind study of the use of droperidol for conscious sedation during therapeutic endoscopy in difficult to sedate patients. Gastrointest Endosc. 2000; 51: 546551
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (42)
Rizzo, J., Bernstein, D., and Gress, F. A randomized double-blind placebo-controlled trial evaluating the cost-effectiveness of droperidol as a sedative premedication for EUS. Gastrointest Endosc. 1999; 50: 178182
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (13)
Yimcharoen, P., Fogel, E.L., Kovacs, R.J. et al. Droperidol, when used for sedation during ERCP, may prolong the QT interval. Gastrointest Endosc. 2006; 63: 979985
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (14)
Gan, T.J. Black box warning on droperidol: report of the FDA convened expert panel. Anesth Analg. 2004; 98: 1809
View in Article | Crossref | PubMed
Young, D. FDA advisory panel discusses droperidol concerns. (22)Am J Health Sys Pharm. 2004; 61: 219220
View in Article | PubMed
Tu, R.H., Grewall, P., Leung, J.W. et al. Diphenhydramine as an adjunct to sedation for colonoscopy: a double-blind randomized, placebo-controlled study. Gastrointest Endosc. 2006; 63: 8794
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (33)
Cohen, L.B., Hightower, C.D., Wood, D.A. et al. Moderate level sedation during endoscopy: a prospective study using low-dose propofol, meperidine/fentanyl, and midazolam. Gastrointest Endosc. 2004; 59: 795803
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (159)
Rex, D.K., Overley, C., Kinser, K. et al. Safety of propofol administered by registered nurses with gastroenterologist supervision in 2000 endoscopic cases. Am J Gastroenterol. 2002; 97: 11591163
View in Article | Crossref | PubMed
Heuss, L.T., Schnieper, P., Drewe, J. et al. Risk stratification and safe administration of propofol by registered nurses supervised by the gastroenterologist: a prospective observational study of more than 2000 cases. Gastrointest Endosc. 2003; 57: 664671
View in Article | Abstract | Full Text | Full Text PDF | PubMed
Cohen, L.B., Delegge, M.H., Aisenberg, J. et al. AGA Institute review of endoscopic sedation. Gastroenterology. 2007; 133: 675701
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (228)
Sieg, A., Hachmoeller-Eisenbach, U., and Eisenbach, T. Prospective evaluation of complications in outpatient GI endoscopy: a survey among German gastroenterologists. Gastrointest Endosc. 2001; 53: 620627
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (213)
Rex, D.K., Heuss, L.T., Walker, J.A. et al. Trained registered nurses/endoscopy teams can administer propofol safely for endoscopy. Gastroenterology. 2005; 129: 13841391
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (205)
Sieg, A., Beck, S. et al. Safety analysis of endoscopist-directed propofol sedation: a prospective, national multicenter study of 24 441 patients in German outpatient practices. J Gastroenterol Hepatol. 2014; 29: 517523
View in Article | Crossref | PubMed | Scopus (30)
Ulmer, B.J., Hansen, J.J., Overley, C.A. et al. Propofol versus midazolam/fentanyl for outpatient colonoscopy: administration by nurses supervised by endoscopists. Clin Gastroenterol Hepatol. 2003; 1: 425432
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (146)
Sipe, B.W., Rex, D.K., Latinovich, D. et al. Propofol versus midazolam/meperidine for outpatient colonoscopy: administration by nurses supervised by endoscopists. Gastrointest Endosc. 2002; 55: 815825
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (253)
Dumonceau, J.M., Riphaus, A., Aparicio, J.R. et al. European Society of Gastrointestinal Endoscopy, European Society of Gastroenterology and Endoscopy Nurses and Associates, and the European Society of Anaesthesiology Guideline: Non-anesthesiologist administration of propofol for GI endoscopy. Endoscopy. 2010; 42: 960974
View in Article | Crossref | PubMed | Scopus (134)
Qadeer, M.A., Vargo, J.J., Khandwala, F. et al. Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis. Clin Gastroenterol Hepatol. 2005; 3: 10491056
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (165)
Levitzky, B.E., Lopez, R., Dumot, J.A. et al. Moderate sedation for elective upper endoscopy with balanced propofol versus fentanyl and midazolam alone: a randomized clinical trial. Endoscopy. 2012; 44: 1320
View in Article | Crossref | PubMed | Scopus (23)
US National Library of Medicine. Propofol. Available at: http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3d382e4e-dab1-47d6-a509-49f5f38bfbfe. Accessed June 14, 2015.
VanNatta, M.E. and Rex, D.K. Propofol alone titrated to deep sedation versus propofol in combination with opioids and/or benzodiazepines and titrated to moderate sedation for colonoscopy. Am J Gastroenterol. 2006; 101: 22092217
View in Article | Crossref | PubMed | Scopus (141)
Khiani, V.S., Soulos, P., Gancayco, J. et al. Anesthesiologist involvement in screening colonoscopy: temporal trends and cost implications in the Medicare population. Clin Gastroenterol Hepatol. 2012; 10: 5864
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (35)
Tetzlaff, J.E., Vargo, J.J., and Maurer, W. Nonoperating room anesthesia for the gastrointestinal endoscopy suite. Anesthesiol Clin. 2014; 32: 387394
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (1)
American Society of Anesthesiology. Statement on anesthesia care for endoscopic procedures 2014. Available at https://www.asahq.org/For-Members/Standards-Guidelines-and-Statements.aspx. Accessed June 14, 2015.
Practice guidelines for postanesthetic care: a report by the American Society of Anesthesiologists Task Force on Postanesthetic Care. Anesthesiology. 2002; 96: 742752
View in Article | Crossref | PubMed | Scopus (134)
Lara, L.F., Ukleja, A., Pimentel, R. et al. Effect of a quality program with adverse events identification on airway management during overtube-assisted enteroscopy. Endoscopy. 2014; 46: 927932
View in Article | Crossref | PubMed | Scopus (6)
Ootaki, C., Stevens, T., Vargo, J. et al. Does general anesthesia increase the diagnostic yield of endoscopic ultrasound-guided fine needle aspiration of pancreatic masses?. Anesthesiology. 2012; 117: 10441050
View in Article | Crossref | PubMed | Scopus (8)
Edgcombe, H., Carter, K., and Yarrow, S. Anaesthesia in the prone position. Br J Anaesth. 2008; 100: 165183
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (187)
Cooper, G.S., Kou, T.D., and Rex, D.K. Complications following colonoscopy with anesthesia assistance: a population-based analysis. JAMA Int Med. 2013; 173: 551556
View in Article | Crossref | PubMed | Scopus (102)
Vargo, J.J., Nikliewski, P.J., Williams, J.L. et al. Patient safety by anesthesia professionals during routine upper endoscopy and colonoscopy: an analysis of 1.38 million procedures. Gastrointest Endosc. 2017; 85: 101108
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (12)
Wernli, K.J., Brenner, A.T., Rutter, C.M. et al. Risks associated with anesthesia services during colonoscopy. Gastroenterology. 2016; 150: 888894
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (43)
Liu, H., Waxman, D.A., Main, R. et al. Utilization of anesthesia services during outpatient endoscopies and colonoscopies and associated spending in 2003-2009. JAMA. 2012; 307: 11781184
View in Article | Crossref | PubMed | Scopus (87)
Inadomi, J.M., Gunnarsson, C.L., Rizzo, J.A. et al. Projected increased growth rate of anesthesia professional-delivered sedation for colonoscopy and EGD in the United States from 2009-2015. Gastrointest Endosc. 2010; 72: 580586
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (57)
Hassan, C., Rex, D.K., Cooper, G.S. et al. Endoscopist-directed propofol administration versus anesthesiologist assistance for colorectal cancer screening: a cost-effectiveness analysis. Endoscopy. 2012; 44: 456464
View in Article | Crossref | PubMed | Scopus (28)
Dominitz, J.A., Baldwin, L.M., Green, P. et al. Regional variation in anesthesia assistance during outpatient colonoscopy is not associated with differences in polyp detection or complication rates. Gastroenterology. 2013; 144: 298306
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (20)
K羹lling, D., Fantin, A.C., Biro, P. et al. Safer colonoscopy with patient-controlled analgesia and sedation with propofol and alfentanil. Gastrointest Endosc. 2001; 54: 17
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (107)
Ng, J.M., Kong, C.F., and Nyam, D. Patient-controlled sedation with propofol for colonoscopy. Gastrointest Endosc. 2001; 54: 813
View in Article | Abstract | Full Text | Full Text PDF | PubMed | Scopus (95)
Heuss, L.T., Drewe, J., Schnieper, P. et al. Patient-controlled versus nurse-administered sedation with propofol during colonoscopy: a prospective randomized trial. Am J Gastroenterol. 2004; 99: 511518
View in Article | Crossref | PubMed | Scopus (74)
Title :
Guidelines for sedation and anesthesia in GI endoscopy
Doi org link :
http://dx.doi.org/10.1016/j.gie.2017.07.018
Volume :
Gastrointest Endosc 2018; Volume 87, Issue 2; P327-337
URL :
Select a choice :
Keep
Content created :
Jan 3, 2018, 07:18 AM
File size :
Number :
ExternalPK :
Categories :
- ERCP/Cholangioscopy
- Lower GI
- Preparation for Endoscopy
- Sedation
- Upper GI
Tags :
- EUS
- Lower GI
- sedation
- Upper GI